Resume
Wang Wei
Professor of Orthopedics and Joints Surgery
Research Areas
Bone and joint disease, Osteoarthritis, Femoral head necrosis treatment, Using 3D printing and digital Orthopedics to achieve precise and individualized knee and hip joint replacement.
E-mail:dr.wangwei@xjtu.edu.cn
Experience and Appointments
- A Chief Physician and a PhD Supervisor.
- Holding Doctor of Medicine degree and a Postdoctoral Fellow.
- Visiting Scholar in Joint Surgery at Harvard Medical School, USA.
- Deputy Director of the Research Department of the Second Affiliated Hospital of Xi'an Jiaotong University.
- Member of the Sports Medicine Branch of the Chinese Medical Doctor Association.
- Member of the Osteoporosis Group of the Orthopedic Branch of the Chinese Medical Association.
- Deputy Head of the Surgery Standard Chemistry Group of the Orthopedic Branch of the Chinese Medical Doctor Association.
- Member of the 3D Printing Orthopedics Group of the Orthopedic Branch of the Chinese Medical Doctor Association.
- Shaanxi Provincial Orthopaedic Branch Chairman of the Medical-Engineering Intersection and Clinical Research Branch of the Joint Society.
- Deputy Director of the Shaanxi Provincial Clinical Research Center for Endemic Diseases.
- Standing Committee Member of the Shaanxi Provincial Working Committee of the Digital Orthopaedic Society of SICOT China.
- Member of the Youth Committee of the Shaanxi Joint Surgery Branch, and Limb of the Orthopedic Branch of the Chinese Medical Doctor Association Member of the Reconstruction Committee.
- Member of the IIIizarov Technical Group of the Physical Disability Rehabilitation Professional Committee of the China Disabled Persons Rehabilitation Association.
- Member of the Osteoporosis Branch of Xi'an Medical Association.
- Expert of Medical Malpractice Appraisal Expert Database of Xi'an Medical Association.
- Member of Youth Editorial Board of BMJ Q&S Chinese Edition in Xincheng District of Xi'an City.
- Editor of Evidence-Based Clinical Diagnosis and Treatment Guidelines for Chinese Artificial Joint Replacement Pain Management.
- Reviewer of National Natural Science Foundation of China.
- Reviewer of The Journal of Rheumatology Manuscript expert.
- BMC Surgery reviewer.
- Chinese Journal of Clinicians (electronic version) reviewer and special editor.
- UpToDate clinical consultant Chinese translation expert.
Education
- December 2007 PhD Surgery, Xi’an Jiaotong University.
- December 2009 - May 2013, Postdoctoral fellow in Mechanical Engineering and Orthopedic Prosthesis, Xi'an Jiaotong University.
- January 2012 to January 2013, Visiting Scholar in Joint Surgery at Massachusetts
- General Hospital affiliated to Harvard Medical School.
Publications
1. Hu Shugang, Meng Zijie, Zhou Junpeng, Li Yongwei, Su Yanwen,Lei Qi, Mao Mao, Qu Xiaoli, He Jiankang*, Wang Wei*. Enhanced Attachment and Collagen Type I Deposition of MC3T3-E1 Cells via Electrohydrodynamic Printed Sub-Microscale Fibrous Architectures. International Journal of Bioprinting, 2022.春季, 8(2): 514 (SCI 6.638/Q1)
2. Li Yongwei, He Jiahui, Zhou Junpeng, Li Zhenlong, Liu Liying, Hu Shugang, Guo Baolin*, Wang Wei* . A conductive photothermal non-swelling nanocomposite hydrogel patch accelerating bone defect repair. Biomaterials Science, 2022, 10(5): 1326-1341. (SCI 6.843/Q1)
3. Liying Liu , Jidong Song , Jun Li , Na Huang , Juan Yang , Shugang Hu , Rui Ma , Wei Wang*.Isoform 1 of Fibrinogen Alpha Chain Precursor is a Potential Biomarker for Steroid-Induced Osteonecrosis of the Femoral Head. Proteomics Clin Appl. 2020 Jul 17;e1900099. (SCI IF=2.489)
4. Wang W, Yan S, Liu F, Chai W, Zuo J, Xiao J, Niels-Derrek S, Zhu Q, Sanghita B, Bogdan I, Wang K. A symmetric anchor designed barbed suture versus conventional interrupted sutures in total knee arthroplasty: A multicenter, randomized controlled trial. J Orthop Surg (Hong Kong). 2020 Sep-Dec;28(3):2309499020965681. (SCI IF=1.095)
5. Song, Jidong; Liu, Liying; Lv, Leifeng; Hu, Shugang; Tariq,Alkhatatbeh;
Wang, Wei*; Dang, Xiaoqian*.Fluid shear stress induces Runx2 expression via upregulation of PIEZO1 in MC3T3-E1 cells. Cell Biology International, 2020 Jul;44(7):1491-1502. (SCI IF=2.172)
6. Rui Ma , Jialin Wang , Chengxin Li , Kai Ma , Jie Wei , Pei Yang , Dagang Guo , Kunzheng Wang* , Wei Wang* .Effects of different sulfonation times and post-treatment methods on the characterization and cytocompatibility of sulfonated PEEK. J Biomater Appl. 2020 Sep;35(3):342-352.(SCI IF=2.220)
7. Ma R, Li Y, Wang J, Yang P, Wang K, Wang W*. Incorporation of nanosized calcium silicate improved osteointegration of polyetheretherketone under diabetic conditions. J Mater Sci Mater Med. 2020 Oct 31;31(11):98. (SCI IF=3.896)
8. Rui Ma,Wei Wang,Pei Yang,Chunsheng Wang,Dagang Guo,Kunzheng Wang*.In vitro antibacterial activity and cytocompatibility of magnesium-incorporated poly(lactide-co-glycolic acid) scaffolds. Biomed Eng Online. 2020 Feb 18;19(1):12. (SCI IF= 2.059)
9. Wang W, Yang K, Yang P, Song D, Wang C, Song J, Li X, Wang K. Primary total knee arthroplasty for complex supracondylar femoral fractures in patients with kneearthritis: A retrospective study of a patient cohort. [J] Medicine (Baltimore). 2018 Oct;97(40):e12700.(SCI IF=2.028)
10. Wang W, Yue B, Wang J, Bedair H, Rubash H, Li G. Posterior Condyle Offset and Maximum Knee Flexion Following a Cruciate Retaining Total Knee Arthroplasty [J] J Knee Surg. 2018 Mar 7. doi: 10.1055/s-0038-1636912.(SCI IF=2.079)
11. Wei Wang, Wei Hu, Yang Pei, Dang XiaoQian, Wang KunZheng . Patient-Specific Core Decompression Surgery for Early-stage Ischemic Necrosis of the Femoral Head [J] PLOS ONE. 2017 May 2;12(5):e0175366.(SCI IF=3.057)
12. Liu L, Wang W, Zhao L Y, et al. Silencing of PLK2 increases cell proliferation and decreases apoptosis in gastric cancer SGC-7901 cells [J]. Molecular Medicine Reports, 2015,11(4):3033-3038. (SCI IF=1.692)
13. Liu L, Wang W, Zhao L, et al. Mir-126 inhibits growth of SGC-7901 cells by synergistically targeting the oncogenes PI3KR2 and Crk, and the tumor suppressor PLK2 [J]. Int J Oncol, 2014, 45(3):1257-1265. (SCI IF=3.333)
14. Wei Wang , Tsung-Yuan Tsa, Bin Yue , Young-Min Kwon , Guoan Li. Posterior femoral condylar offsets of a Chinese population[J].The Knee . 2014 Mar;21(2):553-6. (SCI IF=2.02)
15. Wei Wang，Liying Liu, Xiaoqian Dang, Shuqiang Ma, Mingyu Zhang and Kunzheng Wang. The effect of core decompression on local expression of BMP-2, PPAR-γ and bone regeneration in the steroid-induced femoral head osteonecrosis[J] . BMC Musculoskeletal Disorders , 2012 Aug 9;13:142. (SCI IF=1.88)
16. Wang W, Chen L, Zhang C, Yu Q, Wang K. Experimental study on osteogenic differentiation of adipose-derived stem cells treated with different concentrations of dexamethasone. [J]。Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi.，2011.25(12)：1486-1492
17. WANG wei, WANG Kun-zheng, DANG Xiao-qian,et al.Influencing factors analysis of spontaneous knee joint osteoarthritis among middle aged and old aged pople in Xi'an[J].Journal of Medical Colleges of PLA, 2007,22(3):179-184.
18. Wei Wang , Bin Yue , Guoan Li .Differences in Geometric Features of Distal Femur of Eastern and Western Populations. America Orthopaedic Research Society 2013 Annual Meeting.2013.1.29
19. Ma R, Wu M, Li Y, Wang J, Yang P, Chen Y, Wang W, Song J, Wang K.The use of bone turnover markers for monitoring the treatment of osteoporosis in postmenopausal females undergoing total knee arthroplasty: a prospective randomized study.J Orthop Surg Res. 2021 Mar 17;16(1):195.
20. Ma R, Wu M, Li Y, Wang J, Wang W, Yang P, Wang K.The comparative efficacies of intravenous administration and intra-articular injection of tranexamic acid during anterior cruciate ligament reconstruction for reducing postoperative hemarthrosis: a prospective randomized study.BMC Musculoskelet Disord. 2021 Jan 26;22(1):114.
21. Song J, Zhang R, Lv L, Liang J, Wang W, Liu R, Dang X.The Relationship Between Body Mass Index and Bone Mineral Density: A Mendelian Randomization Study.Calcif Tissue Int. 2020 Nov;107(5):440-445.
22. 李永伟,周俊鹏,胡书刚,王家麟,王坤正,王伟*.提高水凝胶机械性能的方法及其在骨组织工程中的研究进展[J].中国修复重建外科杂志,2021,35(12):1615-1622.
23.王伟,杨佩,王坤正,宋金辉.严重的膝关节冠状面畸形初次膝关节置换应对策略[J].中国骨与关节杂志,2016(10):721-725.
24. 宋丹丹,宋继东,杨琨,李军,王坤正*,王伟*.全膝关节置换术前麻醉前、后膝关节活动度与术后膝关节屈曲功能相关性研究 [J].中国医师杂志,2018(3):324-326.
25.张子琦,李海涛,杨佩,王春生,党晓谦,王坤正*,王伟* .单髁置换术治疗单纯膝关节内侧间室骨性关节炎的短期疗效观察及并发症分析[J].中国医师杂志,2018(3):327-331
26.王伟,刘颖,杨佩,党晓谦,王栋,张纯,刘原* .文献阅读在骨科临床医学专业学位研究生规范化培训中的作用[J].中华医学教育探索杂志,2017(12):1189-1192。
27. 刘志国,余国勇,杨伟兵,户刚,杨登峰,张勇智,阮文辉,王伟* .对侧锁骨远端解剖锁定钢板在患侧锁骨近端骨折并胸锁关节脱位治疗中的应用[J].中国医师杂志，2018(2)270-271。
28.王伟，胡伟，李晓会，党晓歉;Mimics软件三维重建股骨头坏死模型模拟髓芯减压治疗早期股骨头坏死[J]。中华关节外科杂志(电子版)，2013，7(2)。
29. 陈磊杰，王伟，党晓谦，王坤正;脂肪干细胞在骨科基础研究中的新进展;《中国组织工程研究与临床康复》，2011.15(19):3586-3589
30. Wang W, Chen L, Zhang C, Yu Q, Wang K.Experimental study on osteogenic differentiation of adipose-derived stem cells treated with different concentrations of dexamethasone.Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2011 Dec;25(12):1486-92.
31.王伟，王坤正，刘利英，等。激素性股骨头坏死股骨头内PPARγ及BMP2的动态表达[J]。中华骨科杂志，2008. 28(4): 327-332。
32.王伟，王坤正，党小谦，等。中老年人人群骨关节炎的流行病学研究[J]。中国老年杂志，2007，27(3)：566-568。
33.王伟，刘利英，王坤正，等。激素性股骨头坏死模型的建立及其发病机理的探讨[J]。西安交通大学学报(医学版)，2007，28(5)：552-555。
34.王伟，王坤正，党小谦，等。中老年膝骨关节炎发病的相关因素[J]。中国临床康复，2006，10(44)：15-18。
Research Projects
- National Natural Science Foundation of China General Project: Global Core Decompression Implantation of Micro-nano Bionics to Promote In Situ Bone Repair in Necrosis of Femoral Head 2021.01 - 2024.12 Project No.: 82072522 550,000 RMB. Project Principal. In research.
- Shaanxi Province Colleges and Universities Joint Medical-Industrial Cross-Project: Research and Application of "Digital-Magnetic-Net" Intelligent Diagnosis and Treatment Technology for Knee Replacement for Kashin-Beck Disease . Project Principal. In research.
- State Administration of Traditional Chinese Medicine Clinical Collaborative Innovation Project of Integrated Traditional Chinese and Western Medicine: Research on the Clinical Collaborative Diagnosis and Treatment Plan for Elderly Knee Osteoarthritis by Integrated Traditional Chinese and Western Medicine.
- Shaanxi Provincial Administration of Traditional Chinese Medicine Clinical Collaborative Innovation Project of Integrated Traditional Chinese and Western Medicine: Research on the Clinical Collaborative Diagnosis and Treatment Plan for Elderly Knee Osteoarthritis by Integrated Traditional Chinese and Western Medicine. research.
- Key R&D Program of Shaanxi Province General Project: Individualized multi-dimensional duct precise core decompression combined with 3D printing bioactive ceramic microspheres for the treatment of femoral head necrosis 2018.08- 2020.12 150,000 Project leader In research.
- National Key R&D Program Sub-project : The establishment of a large database of Chinese bones and the research on the bone mineral density detection model based on biplane X-ray 2019.12-2021.12 Under research 100,000 RMB.
- National Natural Science Foundation of China General Project: Precise injection of 3D printing navigation template into vascularized bone cement for individualized treatment of femoral head necrosis and collapse 2015-01 to 2018-12 Project number: 81472068 610,000 RMB Project host The project has been completed.
- Interdisciplinary Research Fund of Xi'an Jiaotong University: Structural design and manufacture of vasoactive injectable composite calcium phosphate bone cement with variable stiffness 2015.01-2017.01 Project No.: xjj2014150 100,000 RMB Project Moderator Completed
- Special Fund for Talents Training of the Second Affiliated Hospital of Xi'an Jiaotong University: Biomechanical analysis of injection of self-curing calcium phosphate bone cement in the treatment of femoral head necrosis and collapse
- National Health and Family Planning Commission Key Clinical Special Research Project Horizontal Project: Analysis and Study of Perioperative Safety and Effectiveness of Joint Replacement First Participant Completed
- Additional topics: A prospective, multicenter, randomized controlled study to evaluate the efficiency of incision closure with STRATAFIXTM Symmetric PDSTM Plus absorbable surgical sutures compared with conventional sutures in total knee arthroplasty (TKA). 150,000 RMB, he was the first participants who have completed the question.
- The 49th batch of China Postdoctoral Science Foundation: Variable stiffness structural design and active bone tissue reconstruction in the collapsed area of femoral head necrosis, 2011.6-2013.6. Project host, completed.
- Shaanxi Provincial Science and Technology Project: Tetracycline regulation-rhN455T GDF5 system induces adipose stem cells to differentiate into chondrocytes. 2011.1-2012. 120000 RMB. Project moderator, the question has been closed.
- Interdisciplinary Research Fund of Xi'an Jiaotong University: Computer Aided Design - Rapid Prototyping Technology Assisted Individualization, Precise Core Decompression for the Treatment of Early Femoral Head Necrosis, 2011.1-2012.12. Project No.: 08143027,700,000 RMB, project leader, completed.
- Xi'an Jiaotong University Medical Innovation Fund: rhN445T GDF5 transfected adipose stem cells complex reverse engineering and rapid prototyping technology to prepare cartilage scaffolds and in vivo culture to prepare engineered cartilage.
- National Eleventh Five-Year Plan Project, Horizontal Project: Research on Intervention and Control of Osteoarthritis, 2006.12-2009.12, Project No.: 2006BAI02B02, 450,000 RMB, 4th complete person, completed.
- National 15th scientific and technological research project, horizontal project: Research on osteoarthritis among middle-aged and elderly people in China, 2004.5-2005.12, project number: 2004BA702B06, 180,000 RMB, the fourth person to complete, has been completed.
Patents
1- Core decompression navigator and core decompression method. Wang Wei; Li Dichen; Dang Xiaoqian; Hu Wei. Invention patent, patent number: 201210004387.9; publication number: CN201210004387.9.
2- A core decompression navigation system. Wang Wei; Li Dichen; Dang Xiaoqian; Hu Wei.
Utility model patent, patent number: 201220005714.8; publication number: ZL 2012 2 0005714.8
3- A double C-arm X-ray device. Wang Wei, Li Jun, Yan Bo, Song Jidong Utility model patent, patent number: 201821424017X
4- A wearable walking aid for patients with lower extremity osteoarthropathy. Wang Wei. Invention patent, patent number: 201810037466.7
5- Application of FGA, a steroid-induced femoral head necrosis serum marker. Wang Wei; Liu Liying; Yang Juan. Invention patent, patent number: 201910691276.1
6- A measurement system and measurement method for the angle of the lower limb force line. Wang Wei; Yang Pengfei; Wang Jialin; Yan Junlan. Invention patent, patent number: 202111275455.0; publication number:
