PERSONAL INFORMATION
Name: Tie Chong, MD, Ph.D.
Gender: male Date of birth: 08/25/1967
Chief physician/ professor
Department of Urology,
The Second Affiliated Hospital of Xi’an Jiaotong University,
Xi’an, Shaanxi, China
E-mail: chongtie@126.com
EDUCATION
5/2005-10/2005Visiting scholar: Midlands Centre for Spinal Injuries, Robert Jones and Agnes Hunts Orthopaedic Hospital; Belgium Antwerp University; and Austria Innsbruck University
9/2001-7/2007Doctor degree in Surgery, School of Medicine, Xi’an Jiaotong University, Xi’an, China
9/1992-7/1995Master Degree in Surgery, School of Medicine, Xi’an Jiaotong University, Xi’an, China
9/1985-7/1990Bachelor Degree in Clinical Medicine, School of Medicine, Xi’an Jiaotong University, Xi’an, China
PROFESSIONAL EXPERIENCES
3/2018-presentChief physician, Professor, Chief of the Department of Urology, Chief of the Department of Surgery, Department of Urology, the Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China
09/2011-2/2018Chief physician, Professor, Chief of the Department of Urology, Department of Urology, the Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China
12/2006-8/2011Chief physician, Deputy chief of the Department of Urology, Department of Urology, the Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China
6/2001-11/2006Deputy chief physician, Department of Urology, the Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China
6/1996-5/2001Attending physician, Department of Urology, the Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China
7/1990-5/1996Resident physician, Department of Urology, the Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China
MEMBERSHIP
1. Standing Committee member of Urology Branch of Chinese Medical Association
2. Standing Committee member of Urology Branch of Chinese Medical Doctor Association
3. Chairman Committee member of Urology Branch of Shaanxi province Medical Association
PUBLICATION (first or corresponding author)
Effect of dual mTOR inhibitor on TGFβ1-induced fibrosis in primary human urethral scar fibroblasts |
Biomedicine & Pharmacotherapy |
2018:1182-1187 |
Inhibition of Recombining Binding Protein Suppressor of Hairless (RBPJ) Impairs the Growth of Prostate Cancer |
Cell Physiol Biochem |
2015;36(5):1982-90 |
Evaluation of biophysical as well as biochemical potential of curcumin and resveratrol during prostate cancer |
J Drug Target |
2020 Jan;28(1):41-45 |
Dynamic changes of different phenotypic and genetic circulating tumor cells as a biomarker for evaluating the prognosis of RCC |
Cancer biology & therapy |
2019;20(4):505-12 |
Dendritic cells serve as a "Trojan horse" for oncolytic adenovirus delivery in the treatment of mouse prostate cancer |
Acta Pharmacol Sin |
2016 Aug;37(8):1121-8 |
Evaluating the clinical significance of SHMT2 and its co-expressed gene in human kidney cancer |
Biological research |
2020 Oct 16 |
Kinesin Motor Protein KIFC1 Is a Target Protein of miR-338-3p and Is Associated With Poor Prognosis and Progression of Renal Cell Carcinoma |
Oncology research |
2018;27(1):125-37 |
The effect of a novel glycolysis-related gene signature on progression, prognosis and immune microenvironment of renal cell carcinoma |
BMC CANCER |
DEC 7 2020 |
Genistein attenuates di (2 ethylhexyl) phthalate-induced testicular injuries via activation of Nrf2/HO 1 following prepubertal exposure |
Int J Mol Med |
2018;41(3):1437-1446 |
Downregulation of microRNA-15a suppresses the proliferation and invasion of renal cell carcinoma via direct targeting of eIF4E |
Oncol Rep |
2017 Oct; 38(4): 1995–2002 |
Identification of angiogenesis-related miRNAs in a population of patients with renal clear cell carcinoma |
Oncol Rep |
2014 Nov;32(5):2061-9 |
Identification of key genes and functions of circulating tumor cells in multiple cancers through bioinformatic |
BMC Medical Genomics |
2020 Sep 24;13(1):140 |
The Effect of Stone Composition on the Efficacy of Retrograde Intrarenal Surgery: Kidney Stones 1-3 cm in Diameter |
J Endourol |
2015 May;29(5):537-41 |
Screening disrupted molecular functions and pathways associated with clear cell renal cell carcinoma using Gibbs sampling |
Comput Biol Chem |
2017 Oct; 70:15-20 |
Clinical application of drug sensitive gene detection in postoperative instillation for non-muscle invasive bladder cancer |
BMC NEPHROLOGY. |
OCT 7 2020 |
TUG1 knockdown inhibits the tumorigenesis and progression of prostate cancer by regulating microRNA-496/Wnt/β-catenin pathway |
Anticancer Drugs |
2020 Jul;31(6):592-600 |
Association of ATG7 Polymorphisms and Clear Cell Renal Cell Carcinoma Risk |
Current molecular medicine |
2019 Feb 27 |
The Significance of Detection of Circulating Tumor Cells and Beclin1 in Peripheral Blood of Patients with Renal Cell Carcinoma |
Crit Rev Eukaryot Gene Expr |
2020;30(6):483-492 |
Rapamycin inhibits formation of urethral stricture in rabbits |
Journal of Pharmacology and Experimental Therapeutics |
2011,338(1):47-52 |
Rapamycin inhibts the growth and collagen production of fibroblase derived from human urehtral scar tissue |
Biomed Research International |
2018(13):1-8 |
TPX2 in human clear cell renal carcinoma: Expression, function and prognostic significance |
Oncol Lett |
2016 May;11(5):3515-3521 |
EZH2 enhances the invasive capability of renal cell carcinoma cells via activation of STAT3 |
Mol Med Rep |
2018, 17(3): 3621-3626 |
A novel anti‑cancer effect of resveratrol: reversal of epithelial‑mesenchymal transition in prostate cancer cells |
Mol Med Rep |
2014 Oct;10(4):1717-24 |
Elevated expression of KIF18A enhances cell proliferation and predicts poor survival in human clear cell renal carcinoma |
EXPERIMENTAL AND THERAPEUTIC MEDICINE |
JUL 2016 |
Anuria and abdominal pain induced by ceftriaxone-associated ureterolithiasis in adults |
Int Urol Nephrol |
2013 Feb;45(1):73-6 |
Bioinformatic screening and identification of downregulated hub genes in adrenocortical carcinoma |
Exp Ther Med |
2020 Sep;20(3):2730-2742 |
Knockdown of prostaglandin reductase 1 (PTGR1) suppresses prostate cancer cell proliferation by inducing cell cycle arrest and apoptosis |
Biosci Trends |
2016 May 23;10(2):133-9 |
Retroperitoneal laparoscopic partial nephrectomy versus radical nephrectomy for clinical t1 renal hilar tumor: comparison of perioperative characteristics and short-term functional and oncologic outcomes |
Journal of Laparoendoscopic & Advanced Surgical Techniques Part A |
2018 |
Transurethral resection in women with symptomatic keratinizing squamous metaplasia of urinary bladder: A retrospective study of 92 cases |
Low Urin Tract Symptoms |
2019 |
The impact of TNFSF14 on prognosis and immune microenvironment in clear cell re-nal cell carcinoma |
Genes Genomics |
2020 Jul 28 |
Low-energy shock wave preconditioning reduces renal ischemic reperfusion injury caused by renal artery occlusion |
Acta Cir Bras |
2017 Jul;32(7):550-558 |
RBPJ contributes to acquired docetaxel resistance in prostate cancer cells |
Molecular & Cellular Toxicology |
2017 , 13 (3) :279-285 |
ADVANTAGE
Our team specializes in the diagnosis and treatment of urinary tumors as well as urinary benign diseases, especially the application and promotion of endoscopic and laparoscopic techniques.
GRANTS (PI: Tie Chong)
1. National Nature Science Foundation of China, 82070716, Study of MSCs exosomes inhibiting urethral fibrosis based on Smads/let-7/TGFβR1 signal axis regulating extracellular matrix remodeling, 2021/01-2024/12, CNY550,000
2. National Nature Science Foundation of China,81770689, Role of mTOR signal pathway in urethral stricture formation and screening of key therapeutic targets,2018/01-2021/12,CNY520,000
3. National Nature Science Foundation of China,30972977, Construction and screening of immunotoxin attenuated Stx1A-anti G250 and experimental study on its antitumor effect and mechanism on renal cell carcinoma,2010/01-2012/12,CNY260,000
4. Natural Science major Research Project of Shaanxi Province, 2016ZDJC-12, Translational medicine study of antifibrotic drugs inhibiting urethral stricture formation, 2016/01-2018/12, CNY300,000
TEACHING ACTIVITIES
2005-present: surgery for medical students, Xi’an Jiaotong University
HONORS AND AWARDS
Science and Technology Progress Award of Shaanxi Province (2021, 2005, 1999):
1. Establishment and application of key technologies for precision diagnosis and treatment of renal cancer;
2. Study on the clinical significance of prostate specific antigen in prostate cancer diagnosis;
3. Study on the mechanisms and biological behaviors of multiple gene products and renal cancer.
